Bioinformatics: Theory and Python Programming
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- Curriculum
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Hello, everyone!
In the Course, you will get through the fundamentals of Genetics up to the Bioinformatics methods and tools (both GUI and Python-based tools) with my modest guidance.
The Course consists of 4 chapters.
In the very beginning, we are about to discuss Fundamentals of Genetics, Central Dogma of Molecular Biology, Nucleotide Sequences as Code, Codons, Proteins and Functional Sequence Elements present in the Genome, in Chapter 1.
Then, in Chapter 2, you will be introduced to Bioinformatics, its goals and different approaches taken by various scientists. You will clearly see the difference between these approaches and take them into account planning your own workflow later. Remember, you are always free to pick your own best combination of tools, using knowledge accumulated.
In Chapter 3, you will learn what data formatting types are present in the bioinformatics field and how they look like, especially the FASTA and PHYLIP formats. You’ll also learn how to work with web-based GUI software and perform conversion between the formats given, and also how to perform BLAST analysis.
In Chapter 4, you will get into Bioinformatics with Biopython and other tools. You will get to understand how to use command-line tools and BioPython library in order to perform BLAST analysis with different settings, create genome visualization with GenomeDiagram library using Genbank formatted genomic data. To put it short, you will be able to simply make your work more controllable and sophisticated in terms of specificity.
So, at the end of this course, you will understand what Bioinformatics is, what it is based on and how to organise your workflow understanding the basics of data in this field. You will also get skills of performing sequence formats’ conversions and BLAST analysis, writing python scripts and working in command-line software.
Welcome to the course!
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2
Biomolecules and Bioinformatics (DNA/RNA, nucleotides)Genetic, or hereditary info is stored in the cell as biomolecules like nucleic acids and proteins.
Nucleic acids and genetic information encode and basically drive the development and functioning of the organism, population, thus changing or maintaining the species evolutionary destiny.
Encoding ability of nucleic acids gives us opportunities to decode the resulting proteins and analyse the data derived from it.
It is essential to understand the molecular structure of the basis of life in this context.
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3
Proteins, Functional Nucleotides Sequences
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4
Enhancers and Silencers
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5
Section 1 Test
